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KMID : 0378019810240110099
New Medical Journal
1981 Volume.24 No. 11 p.99 ~ p.102
Therapeutic Effects of Trimebutine Maleate (Polybutine^(¢ç)) to Gastrointestinal symptoms in children


Abstract
Therapeutic effects of Trimebutine were studied for gastrointestinal symptoms in 46 cases of infancy with syrup and 48 cases with tablet and placebo.
Trimebutine was given lml/kg/day of syrup and 5mg/kg/day of tablet, orally, in three divided doses.
The results were as follows
1. Of the 46 cases of infancy with gastrointestinal symptoms who treated with syrup, 36 cases (78. 2%) and 5 cases (10. 9%) showed good and fair responses, respectively.
2. Of the 35 cases of children with gastrointestinal symptoms who treated with tablet, 21 cases(60%) and 10 cases(28.6%) showed good and fair responses, respectively. And placebo group showed good (8.7%) and fair (30.4%) responses only.
3. Any side effect was not noted in all groups.
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